Hello, I've found that the key note i use is one that makes it comfortable for the range of my voice and in a key that is most easy for me to sing in. For the range of my voice a lower pitch might be better if i'm singing alone, but say if playing Kirtan in a group that has a combination of higher and lower voices, an average has to be gotten for the comfort of the different voices in the group. Sometimes higher works better and sometimes lower.
When you say "keynote" do you mean the pitch used as the drone?